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Kottakkal Journal of Ayurvedic Medicine And Research

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

July-September 2025

Volume 1, Issue 3 - undefined null

Volume 1 Issue 3 Cover

Issue Details:

Volume 1 Issue 3
Published:Invalid Date

Editorial: July-September 2025

Welcome to the issue of Kottakkal Journal of Ayurvedic Medicine And Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Margaret Thompson
Editor-in-Chief
Kottakkal Journal of Ayurvedic Medicine And Research

Articles in This Issue

Showing 6 of 6 articles
Research PaperID: KJAMR-00000037

AYURVEDA AND EPIGENETICS: FOUNDATIONS FOR PREVENTIVE AND PRECISION HEALTHCARE

Dr.Aswathy V J, Dr.Subin.V R

The article explores the intersection of Ayurveda and epigenetics, presenting a novel framework for preventive and precision healthcare. Ayurveda, with its holistic principles of Prakriti (individual constitution), Pathya-Apathya (wholesome/ unwholesome), and Swasthavritta (healthy living), provides a rich philosophical and practical base for influencing gene expression. Epigenetics, which studies heritable changes in gene function without DNA sequence alterations, offers mechanistic insights into how environmental factors, lifestyle, diet, and emotional states affect gene expression through DNA methylation, histone modification, and non-coding RNAs. The article elucidates the epigenetic basis of health and disease, highlighting the role of these modifications in conditions like cancer, autoimmune disorders, and neurodegenerative diseases. It draws parallels between Ayurvedic concepts such as Beeja (genetic material), Vikriti (deviation from normalcy), and Garbhini Paricharya (antenatal care), and modern understandings of gene regulation. It emphasizes how Ayurvedic practices—like Dinacharya, Ritucharya, and Garbhopaghatakarabhava—can favorably influence epigenetic outcomes. The emerging field of Ayurgenomics is presented as a bridge between traditional Ayurvedic wisdom and modern genomics, supporting personalized medicine. The article concludes by suggesting that integrating Ayurveda with epigenetic science holds immense potential for advancing individualized health strategies and fostering long-term well-being.

AyurvedaEpigeneticsHealthcare
3,574 views
1,011 downloads

Contributors:

 Dr.Aswathy V J
,
 Dr.Subin.V R
Research PaperID: KJAMR-00000034

EFFECT OF ABHRA NISHADI CHURNA AS ADD -ON MEDICATION ON POST PRANDIAL BLOODSUGAR IN TYPE 2 DIABETES MELLITUS : A CASE REPORT

Dr. Antony Jose

Ayurveda provides detailed knowledge of causative factors and pathogenesis of diseases, along with time tested treatments based on its principles. We report a 10 year chronic case of diabetes mellitus (68-year-old female patient), currently on conventional medicine, having a short time elevation of blood glucose level. A one- month long Ayurveda treatment, along with the present conventional medicine, has shown notable efficacy in managing the hyperglycemia.

Diabetes mellitusHyperglycemiaAbhra nishadi churna
3,250 views
901 downloads

Contributors:

 Dr. Antony Jose
Research PaperID: KJAMR-00000033

EFFECTIVENESS OF BAKUCHI (PSORALEA CORYLIFOLIA LINN.) AS RASAYANA THERAPY IN PSORIASIS - A CASE REPORT

Dr Priya N K, Dr.Binitha.A, Dr. Shabna.P

Psoriasis is a chronic and debilitating disease with a considerable global impact, characterized by increased rates of relapse and remission, significantly affecting the psychosomatic well-being of patients. It is a disease which can produce adverse effects on different tissues including joints and which is also characterised by recurrence after treatment cessation. This is the case study of a 61-year-old male who was a chronic smoker presenting with complaints of itchy, scaly lesions all over the body, especially over face, ears, head, back, bilateral lower limbs and upper limbs for the past 12 years which had aggravated over the last 2 months and consulted OPD of Vaidyaratnam PS Varier Ayurveda College, Kottakkal. The treatment approach adopted in this case of plaque psoriasis was sodhana (biopurification) therapy followed by rasayana (rejuvenation) therapy. The combination of Bakuchi rasayana used here contains only minimal ingredients, yet it is an effective regimen. Also, it has additional benefits like easiness of preparation and palatability. After the full course of treatment there was an overall improvement in symptoms, notable among them were a decrease in PASI score from 14.5 to 4.8, and a significant enhancement in the patient's quality of life. Following the rasayana therapy, the patient was able to pass bowel without straining. Thus, the combination of sodhana therapies followed by the administration of Bakuchi rasayana played a significant role in the marked improvement of lesions in plaque psoriasis.

psoriasisbakuchirasayanaekakushta
2,740 views
918 downloads

Contributors:

 Dr Priya N K
,
 Dr.Binitha.A
,
 Dr. Shabna.P
Research PaperID: KJAMR-00000032

MANAGEMENT OF CHRONIC KIDNEY DISEASE USING AYURVEDIC TREATMENT PROTOCOL

Sreelekshmy Eramangalath, Adwaith B G, Dr. Krishnaveni

Chronic Kidney Disease (CKD) is a multifaceted progressive deterioration of renal function. Its furtherance is often undetected and paves way to a pervasive and insidious health crisis. Methodology: A review of published cases was planned to explore the efficacy of Ayurvedic management in improving renal function and other symptomatic parameters in CKD. A comprehensive literature search of case studies in Google Scholar and PubMed spanning five years was conducted. The studies that fulfilled the inclusive criteria were included in the review. Based on this conclusion, an in-depth interview of five experts treating CKD from Malappuram, Kerala was done. The interpretations of both the review of published case reports on ayurvedic management of CKD and in-depth interview were statistically represented. Result: Out of 22 identified case reports, 14 met the inclusion criteria for analysis. The mean age of the subjects was 51.58 years, with 71.4% males and 26.8% females. Following Ayurvedic treatment, notable improvements were observed in serum creatinine, serum urea and e-GFR. Conclusion: This case based review suggests that Ayurvedic treatment can contribute to improving the quality of life of CKD affected patients. However, inconsistencies in methodology and lack of standardized diagnostic criteria underscore the need for large-scale, high quality clinical trials to confirm these findings and establish the efficacy and safety of Ayurvedic formulations in CKD management.

Chronic kidney diseaseAyurvedaGFRCKD
2,929 views
793 downloads

Contributors:

 Sreelekshmy Eramangalath
,
 Adwaith B G
,
 Dr. Krishnaveni
Research PaperID: KJAMR-00000035

RELATION OF TWAK TO DHATUSAARATHA

Dr Uma Karthik

The skin which forms the largest organ in the body is involved in many homeostatic functions like temperature regulation, Vitamin D synthesis and forms a mechanical barrier against pathogens. It is a site of expression of various normal and abnormal processes in the body. The role of vata, pitta and kapha dosha are important in determining the nature of skin. The excellence of the dhatu is also expressed as healthy skin or dhatusaaratha. Rasasaaratha is equivalent to twaksaaratha. The equivalence of rasa to twak is an important factor in deciding the route of medicine as internal or external in skin disorders.

Twakdhatusaaratharasa
3,072 views
932 downloads

Contributors:

 Dr Uma Karthik
Research PaperID: KJAMR-00000036

ROLE OF GUT MICROBES IN GUT BRAIN AXIS AND ITS IMPLICATIONS IN AYURVEDA - A PILOT STUDY

Dr.Jairam K V, Dr.Basvantarao Patil

Introduction: The gut-brain axis (GBA) refers to the communication between the central and the enteric nervous system in the wall of the GIT. This represents the links between emotional and cognitive centers of the brain with digestive functions. Studies have shown the significant role of gut microbiota in determining and modifying these interactions. Ayurveda and its approach to diagnosis and treatment is influenced by the status of digestive functions in the gut which harbours the gut microbes. Materials and Methods: Online databases including PubMed and Google scholar were searched for articles with keywords - gut brain axis and gut microbiome. A total of 19 articles were listed and 8 were selected from them based on their clarity of methodology, relevance and feasibility. A framework was developed after reviewing and organizing 8 articles, emphasizing the significance of Rukshana Chikitsa in Ayurveda for maintaining the regular functioning of the gut microbiome. These findings were validated using the tool which assesses rukshata-snigdhata in koshta among 10 participants undergoing takrapana and another group of 10 participants undergoing antibiotic therapy. Results and Discussion:73% of participants undergoing takrapana shows healthy koshta, whereas only 27% of participants undergoing antibiotic therapy show healthy koshta. Remaining participants showed increased rukshata in koshta. Koshta is an important part of clinical examination of patient in Ayurveda. The classification of koshta into mrudu, madyama and krura koshta represents a difference in the gut microbial environment. Conclusion: This article reviews the role of Ayurvedic principles like Agni, koshta and panchakarma chikitsa in the communication between the gut-microbiota and the brain through neural, endocrine and immune links as well as their influences on health and disease.

Gut microbesGut brain axisAyurveda
3,327 views
1,108 downloads

Contributors:

 Dr.Jairam K V
,
 Dr.Basvantarao Patil
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